Rhodiola Root Liquid Extract- Try it Free!
Product Description
Rhodiola rosea is an authentic adaptogen, non-specifically increasing the resistance of the body without disturbing its normal biological functions. For that reason, it is a great herb for combating stress. It is theorized that R. rosea improves the brain's ability to deal with stress by increasing serotonin in the hypothalamus and midbrain, increasing endorphins, moderating the release of opioid peptides that occur as a part of the stress response, and protecting the brain and heart by reducing the stress related production of corticotrophin releasing factor (CRF).
It is a wonderful herb for mental focus and cerebral activity. It promotes the release and enhances the effectiveness of neurotransmitters like serotonin, dopamine and norepinephrine in the brain. The results, demonstrated in several clinical studies, are enhanced mental performance, learning, attention span, and memory. It has been widely used as an antidepressant, working alone or adjunctively with other antidepressants. Because of the breadth of its adaptogenic effects, some patients find it more effective than prescription SSRI's or St. John's Wort.
Another beneficial adaptogenic effect of Rhodiola rosea is its ability to increase physical work capacity, improving strength, recovery time, endurance, and coordination. Clinical studies found it to be more effective than Eleuthero at enhancing adaptation to physical stress. Combining the two herbs in a formula is even better, as R. rosea and Eleutherococcus senticosis are very compatible, producing beneficial synergistic effects.
Rhodiola has been shown to enhance fertility in women, even among those that have failed to conceive with standard fertility drugs; and to substantially improve sexual performance in men with erectile dysfunction and/or premature ejaculation. It also enhances thyroid and adrenal function without causing hyperfunction of those organs.
Part of R. rosea's effectiveness as a stress adaptogen is due to its cardioprotective effects. Because it promotes the balanced release of epinephrine and nor epinephrine, it is a very effective anti-arrhythmia/tachycardia agent. It also increases the energy efficiency and energy reserves of the heart by balancing the heart's sympathetic and parasympathetic autonomic nerve inputs.
Additionally, this amazing root is a strong antioxidant with several anti-cancer effects. It reduces the toxicity of anti-cancer drugs and enhances their anti-carcinogenic effects. It helps to inhibit tumor growth on its own, and is also anti-mutagenic, substantially reducing the development of chromosomal aberrations.
R. rosea is very safe with very low toxicity and few side effects.
____________________
Phytomedicine. 2010 Jun;17(7):481-93. Epub 2010 Apr 7.
Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Panossian A, Wikman G, Sarris J.
Swedish Herbal Institute Research and Development, Askloster, Sweden. alexander.panossian@shi.se
Abstract: The aim of this review article was to summarize accumulated information related to chemical composition, pharmacological activity, traditional and official use of Rhodiola rosea L. in medicine. In total approximately 140 compounds were isolated from roots and rhizome - monoterpene alcohols and their glycosides, cyanogenic glycosides, aryl glycosides, phenylethanoids, phenylpropanoids and their glycosides, flavonoids, flavonlignans, proanthocyanidins and gallic acid derivatives. Studies on isolated organs, tissues, cells and enzymes have revealed that Rhodiola preparations exhibit adaptogenic effect including, neuroprotective, cardioprotectiv e, anti-fatigue, antidepressive, anxiolytic, nootropic, life-span increasing effects and CNS stimulating activity. A number of clinical trials demonstrate that repeated administration of R. rosea extract SHR-5 exerts an anti-fatigue effect that increases mental performance (particularly the ability to concentrate in healthy subjects), and reduces burnout in patients with fatigue syndrome. Encouraging results exist for the use of Rhodiola in mild to moderate depression, and generalized anxiety. Several mechanisms of action possibly contributing to the clinical effect have been identified for Rhodiola extracts. They include interactions with HPA-system (cortisol-reducing), protein kinases p-JNK, nitric oxide, and defense mechanism proteins (e.g. heat shock proteins Hsp 70 and FoxO/DAF-16). Lack of interaction with other drugs and adverse effects in the course of clinical trials make it potentially attractive for use as a safe medication. In conclusion, Rhodiola rosea has robust traditional and pharmacological evidence of use in fatigue, and emerging evidence supporting cognition and mood.
____________________
Pol J Vet Sci. 2009;12(3):399-405.
The effect of Chinese medicinal herb Rhodiola kirilowii extracts on cellular immunity in mice and rats. Wójcik R, Siwicki AK, Skopińska-Rózewska E, Wasiutyński A, Sommer E, Furmanowa M.
Department of Microbiology and Clinical Immunology, University of Warmia and Mazury, Oczapowskiego 13, 10-957 Olsztyn, Poland.
Abstract: Rhodiola kirilowii (RK) roots and rhizomes are traditionally used in China as a tonic, adaptogen, antimicrobial and anti-inflammatory drug. The aim of this work was to study the in vivo and in vitro effects of aqueous and 50% hydro-alcoholic extracts of RK rhizomes on some parameters of cellular immunity in H-2d mice and rats. We show for the first time that in vitro both extracts stimulated granulocyte activity and increased lymphocyte response to mitogens, and in vivo they enhanced the ability of lymphocytes derived from parental strain mice fed R. kirilowii aqueous and hydro-alcoholic extracts, to induce local cutaneous graft-versus-host reaction (GVH) in F1 hybrids. Conclusion: Rhodiola kirilowii extracts are cellular immunity enhancers.
____________________
Planta Med. 2009 Feb;75(2):105-12. Epub 2008 Nov 18.
A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Olsson EM, von Schéele B, Panossian AG.
Department of Psychology, Uppsala University, Uppsala, Sweden. erik.olsson@psyk.uu.se
Abstract: The aim of the study was to assess the efficacy of the standardised extract SHR-5 of roots of Rhodiola Rosea L. in the treatment of individuals suffering from stress-related fatigue. The phase III clinical trial took the form of a randomised, double-blind, placebo-controlled study with parallel groups. Participants, males and females aged between 20 and 55 years, were selected according to the Swedish National Board of Health and Welfare diagnostic criteria for fatigue syndrome. A total of 60 individuals were randomised into two groups, one ( N = 30) of which received four tablets daily of SHR-5 extract (576 mg extract/day), while a second ( N = 30) received four placebo tablets daily. The effects of the extract with respect to quality of life (SF-36 questionnaire), symptoms of fatigue (Pines' burnout scale), depression (Montgomery -Asberg depression rating scale - MADRS), attention (Conners' computerised continuous performance test II - CCPT II), and saliva cortisol response to awakening were assessed on day 1 and after 28 days of medication. Data were analysed by between-within analyses of variance. No serious side effects that could be attributed to the extract were reported. Significant post-treatment improvements were observed for both groups (placebo effect) in Pines' burnout scale, mental health (SF-36), and MADRS and in several CCPT II indices of attention, namely, omissions, commissions, and Hit RT SE. When the two groups were compared, however, significant effects of the SHR-5 extract in comparison with the placebo were observed in Pines' burnout scale and the CCPT II indices omissions, Hit RT SE, and variability. Pre- VERSUS post-treatment cortisol responses to awakening stress were significantly different in the treatment group compared with the control group. It is concluded that repeated administration of R. ROSEA extract SHR-5 exerts an anti-fatigue effect that increases mental performance, particularly the ability to concentrate, and decreases cortisol response to awakening stress in burnout patients with fatigue syndrome.
____________________
J Altern Complement Med. 2008 Mar;14(2):175-80.
A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). Bystritsky A, Kerwin L, Feusner JD.
Department of Psychiatry, University of California, Los Angeles, CA, USA. abystritsky@mednet.ucla.edu
Abstract BACKGROUND: Rhodiola rosea is an herbal supplement that many in the general population in Russia and elsewhere in the world have used for decades to alleviate everyday anxiety, depression, and insomnia. Whether R. rosea is effective in reducing similar symptoms in clinical samples is unknown. The goal of this pilot study was to evaluate whether R. rosea is effective in reducing symptoms of generalized anxiety disorder (GAD).
METHOD: Ten (10) participants with a DSM-IV diagnosis of GAD, recruited from the UCLA Anxiety Disorders Program and between the ages of 34 and 55, were enrolled in this study from November 2005 to May 2006. Participants received a total daily dose of 340 mg of R. rosea extract for 10 weeks. Assessments included the Hamilton Anxiety Rating Scale (HARS), the Four-Dimensional Anxiety and Depression Scale, and the Clinical Global Impressions of Severity/Improvement Scale.
RESULTS: Individuals treated with R. rosea showed significant decreases in mean HARS scores at endpoint (t=3.27, p=0.01). Adverse events were generally mild or moderate in severity, the most common being dizziness and dry mouth.
CONCLUSIONS: Significant improvement in GAD symptoms was found with R. rosea, with a reduction in HARS scores similar to that found in clinical trials. These preliminary findings warrant further exploration of treatment with R. rosea in clinical samples.
*Free Trial- Try the product free for 14 days. If you are not satisfied contact customer service to arrange for a return and cancelation and you will not be charged anything. Otherwise, you will be enrolled into our Monthly Rewards program and be charged the discounted price of $25 (regular price $30) plus shipping every month for your commitment. You may cancel at anytime.
It is a wonderful herb for mental focus and cerebral activity. It promotes the release and enhances the effectiveness of neurotransmitters like serotonin, dopamine and norepinephrine in the brain. The results, demonstrated in several clinical studies, are enhanced mental performance, learning, attention span, and memory. It has been widely used as an antidepressant, working alone or adjunctively with other antidepressants. Because of the breadth of its adaptogenic effects, some patients find it more effective than prescription SSRI's or St. John's Wort.
Another beneficial adaptogenic effect of Rhodiola rosea is its ability to increase physical work capacity, improving strength, recovery time, endurance, and coordination. Clinical studies found it to be more effective than Eleuthero at enhancing adaptation to physical stress. Combining the two herbs in a formula is even better, as R. rosea and Eleutherococcus senticosis are very compatible, producing beneficial synergistic effects.
Rhodiola has been shown to enhance fertility in women, even among those that have failed to conceive with standard fertility drugs; and to substantially improve sexual performance in men with erectile dysfunction and/or premature ejaculation. It also enhances thyroid and adrenal function without causing hyperfunction of those organs.
Part of R. rosea's effectiveness as a stress adaptogen is due to its cardioprotective effects. Because it promotes the balanced release of epinephrine and nor epinephrine, it is a very effective anti-arrhythmia/tachycardia agent. It also increases the energy efficiency and energy reserves of the heart by balancing the heart's sympathetic and parasympathetic autonomic nerve inputs.
Additionally, this amazing root is a strong antioxidant with several anti-cancer effects. It reduces the toxicity of anti-cancer drugs and enhances their anti-carcinogenic effects. It helps to inhibit tumor growth on its own, and is also anti-mutagenic, substantially reducing the development of chromosomal aberrations.
R. rosea is very safe with very low toxicity and few side effects.
____________________
Phytomedicine. 2010 Jun;17(7):481-93. Epub 2010 Apr 7.
Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Panossian A, Wikman G, Sarris J.
Swedish Herbal Institute Research and Development, Askloster, Sweden. alexander.panossian@shi.se
Abstract: The aim of this review article was to summarize accumulated information related to chemical composition, pharmacological activity, traditional and official use of Rhodiola rosea L. in medicine. In total approximately 140 compounds were isolated from roots and rhizome - monoterpene alcohols and their glycosides, cyanogenic glycosides, aryl glycosides, phenylethanoids, phenylpropanoids and their glycosides, flavonoids, flavonlignans, proanthocyanidins and gallic acid derivatives. Studies on isolated organs, tissues, cells and enzymes have revealed that Rhodiola preparations exhibit adaptogenic effect including, neuroprotective, cardioprotectiv e, anti-fatigue, antidepressive, anxiolytic, nootropic, life-span increasing effects and CNS stimulating activity. A number of clinical trials demonstrate that repeated administration of R. rosea extract SHR-5 exerts an anti-fatigue effect that increases mental performance (particularly the ability to concentrate in healthy subjects), and reduces burnout in patients with fatigue syndrome. Encouraging results exist for the use of Rhodiola in mild to moderate depression, and generalized anxiety. Several mechanisms of action possibly contributing to the clinical effect have been identified for Rhodiola extracts. They include interactions with HPA-system (cortisol-reducing), protein kinases p-JNK, nitric oxide, and defense mechanism proteins (e.g. heat shock proteins Hsp 70 and FoxO/DAF-16). Lack of interaction with other drugs and adverse effects in the course of clinical trials make it potentially attractive for use as a safe medication. In conclusion, Rhodiola rosea has robust traditional and pharmacological evidence of use in fatigue, and emerging evidence supporting cognition and mood.
____________________
Pol J Vet Sci. 2009;12(3):399-405.
The effect of Chinese medicinal herb Rhodiola kirilowii extracts on cellular immunity in mice and rats. Wójcik R, Siwicki AK, Skopińska-Rózewska E, Wasiutyński A, Sommer E, Furmanowa M.
Department of Microbiology and Clinical Immunology, University of Warmia and Mazury, Oczapowskiego 13, 10-957 Olsztyn, Poland.
Abstract: Rhodiola kirilowii (RK) roots and rhizomes are traditionally used in China as a tonic, adaptogen, antimicrobial and anti-inflammatory drug. The aim of this work was to study the in vivo and in vitro effects of aqueous and 50% hydro-alcoholic extracts of RK rhizomes on some parameters of cellular immunity in H-2d mice and rats. We show for the first time that in vitro both extracts stimulated granulocyte activity and increased lymphocyte response to mitogens, and in vivo they enhanced the ability of lymphocytes derived from parental strain mice fed R. kirilowii aqueous and hydro-alcoholic extracts, to induce local cutaneous graft-versus-host reaction (GVH) in F1 hybrids. Conclusion: Rhodiola kirilowii extracts are cellular immunity enhancers.
____________________
Planta Med. 2009 Feb;75(2):105-12. Epub 2008 Nov 18.
A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Olsson EM, von Schéele B, Panossian AG.
Department of Psychology, Uppsala University, Uppsala, Sweden. erik.olsson@psyk.uu.se
Abstract: The aim of the study was to assess the efficacy of the standardised extract SHR-5 of roots of Rhodiola Rosea L. in the treatment of individuals suffering from stress-related fatigue. The phase III clinical trial took the form of a randomised, double-blind, placebo-controlled study with parallel groups. Participants, males and females aged between 20 and 55 years, were selected according to the Swedish National Board of Health and Welfare diagnostic criteria for fatigue syndrome. A total of 60 individuals were randomised into two groups, one ( N = 30) of which received four tablets daily of SHR-5 extract (576 mg extract/day), while a second ( N = 30) received four placebo tablets daily. The effects of the extract with respect to quality of life (SF-36 questionnaire), symptoms of fatigue (Pines' burnout scale), depression (Montgomery -Asberg depression rating scale - MADRS), attention (Conners' computerised continuous performance test II - CCPT II), and saliva cortisol response to awakening were assessed on day 1 and after 28 days of medication. Data were analysed by between-within analyses of variance. No serious side effects that could be attributed to the extract were reported. Significant post-treatment improvements were observed for both groups (placebo effect) in Pines' burnout scale, mental health (SF-36), and MADRS and in several CCPT II indices of attention, namely, omissions, commissions, and Hit RT SE. When the two groups were compared, however, significant effects of the SHR-5 extract in comparison with the placebo were observed in Pines' burnout scale and the CCPT II indices omissions, Hit RT SE, and variability. Pre- VERSUS post-treatment cortisol responses to awakening stress were significantly different in the treatment group compared with the control group. It is concluded that repeated administration of R. ROSEA extract SHR-5 exerts an anti-fatigue effect that increases mental performance, particularly the ability to concentrate, and decreases cortisol response to awakening stress in burnout patients with fatigue syndrome.
____________________
J Altern Complement Med. 2008 Mar;14(2):175-80.
A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). Bystritsky A, Kerwin L, Feusner JD.
Department of Psychiatry, University of California, Los Angeles, CA, USA. abystritsky@mednet.ucla.edu
Abstract BACKGROUND: Rhodiola rosea is an herbal supplement that many in the general population in Russia and elsewhere in the world have used for decades to alleviate everyday anxiety, depression, and insomnia. Whether R. rosea is effective in reducing similar symptoms in clinical samples is unknown. The goal of this pilot study was to evaluate whether R. rosea is effective in reducing symptoms of generalized anxiety disorder (GAD).
METHOD: Ten (10) participants with a DSM-IV diagnosis of GAD, recruited from the UCLA Anxiety Disorders Program and between the ages of 34 and 55, were enrolled in this study from November 2005 to May 2006. Participants received a total daily dose of 340 mg of R. rosea extract for 10 weeks. Assessments included the Hamilton Anxiety Rating Scale (HARS), the Four-Dimensional Anxiety and Depression Scale, and the Clinical Global Impressions of Severity/Improvement Scale.
RESULTS: Individuals treated with R. rosea showed significant decreases in mean HARS scores at endpoint (t=3.27, p=0.01). Adverse events were generally mild or moderate in severity, the most common being dizziness and dry mouth.
CONCLUSIONS: Significant improvement in GAD symptoms was found with R. rosea, with a reduction in HARS scores similar to that found in clinical trials. These preliminary findings warrant further exploration of treatment with R. rosea in clinical samples.
*Free Trial- Try the product free for 14 days. If you are not satisfied contact customer service to arrange for a return and cancelation and you will not be charged anything. Otherwise, you will be enrolled into our Monthly Rewards program and be charged the discounted price of $25 (regular price $30) plus shipping every month for your commitment. You may cancel at anytime.